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Identification of Critical Residues of Linear B Cell Epitope on Goodpasture Autoantigen

BACKGROUND: The autoantigen of anti-glomerular basement membrane (GBM) disease has been identified as the non-collagenous domain 1 of α3 chain of type IV collagen, α3(IV)NC1. Our previous study revealed a peptide on α3(IV)NC1 as a major linear epitope for B cells and potentially nephrogenic, designa...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Jia, Xiao-yu, Cui, Zhao, Li, Jian-nan, Hu, Shui-yi, Zhao, Ming-hui
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395375/
https://ncbi.nlm.nih.gov/pubmed/25874890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123277
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