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Identification of Critical Residues of Linear B Cell Epitope on Goodpasture Autoantigen
BACKGROUND: The autoantigen of anti-glomerular basement membrane (GBM) disease has been identified as the non-collagenous domain 1 of α3 chain of type IV collagen, α3(IV)NC1. Our previous study revealed a peptide on α3(IV)NC1 as a major linear epitope for B cells and potentially nephrogenic, designa...
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Publicado no: | PLoS One |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4395375/ https://ncbi.nlm.nih.gov/pubmed/25874890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123277 |
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