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MiR-375 Promotes Redifferentiation of Adult Human β Cells Expanded In Vitro

In-vitro expansion of β cells from adult human pancreatic islets could provide abundant cells for cell replacement therapy of diabetes. However, proliferation of β-cell-derived (BCD) cells is associated with dedifferentiation. Here we analyzed changes in microRNAs (miRNAs) during BCD cell dedifferen...

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Pubblicato in:PLoS One
Autori principali: Nathan, Gili, Kredo-Russo, Sharon, Geiger, Tamar, Lenz, Ayelet, Kaspi, Haggai, Hornstein, Eran, Efrat, Shimon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395232/
https://ncbi.nlm.nih.gov/pubmed/25875172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122108
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