Heterogeneity of Genetic Pathways toward Daptomycin Nonsusceptibility in Staphylococcus aureus Determined by Adjunctive Antibiotics

Daptomycin is increasingly used in combination with other antibiotics to enhance antimicrobial efficacy and/or to mitigate the emergence of daptomycin nonsusceptibility (DNS). This study used a clinical methicillin-resistant Staphylococcus aureus (MRSA) strain in which DNS emerged upon therapy to ex...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Berti, Andrew D., Baines, Sarah L., Howden, Benjamin P., Sakoulas, George, Nizet, Victor, Proctor, Richard A., Rose, Warren E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394801/
https://ncbi.nlm.nih.gov/pubmed/25733508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04990-14
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