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Serial Daptomycin Selection Generates Daptomycin-Nonsusceptible Staphylococcus aureus Strains with a Heterogeneous Vancomycin-Intermediate Phenotype

In order to better understand the mechanism of daptomycin resistance, we generated a daptomycin-nonsusceptible derivative strain, strain 10*3d1 (MIC = 3.0 μg/ml), by in vitro exposure of methicillin-resistant Staphylococcus aureus strain N315ΔIP (MIC = 0.5 μg/ml) to daptomycin. We also obtained a da...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Camargo , Ilana Lopes Baratella da Cunha, Neoh, Hui-Min, Cui, Longzhu, Hiramatsu, Keiichi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592861/
https://ncbi.nlm.nih.gov/pubmed/18824611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00417-08
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