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Serial Daptomycin Selection Generates Daptomycin-Nonsusceptible Staphylococcus aureus Strains with a Heterogeneous Vancomycin-Intermediate Phenotype
In order to better understand the mechanism of daptomycin resistance, we generated a daptomycin-nonsusceptible derivative strain, strain 10*3d1 (MIC = 3.0 μg/ml), by in vitro exposure of methicillin-resistant Staphylococcus aureus strain N315ΔIP (MIC = 0.5 μg/ml) to daptomycin. We also obtained a da...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592861/ https://ncbi.nlm.nih.gov/pubmed/18824611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00417-08 |
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