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Combination of the R263K and M184I/V Resistance Substitutions against Dolutegravir and Lamivudine Decreases HIV Replicative Capacity
We investigated the effect of combining the dolutegravir-specific R263K integrase resistance substitution with either M184I or M184V, two reverse transcriptase drug resistance substitutions that are frequently detected in individuals failing therapeutic regimens containing either lamivudine or emtri...
Gespeichert in:
| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394770/ https://ncbi.nlm.nih.gov/pubmed/25666155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05181-14 |
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