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Constant pH Molecular Dynamics of Proteins in Explicit Solvent with Proton Tautomerism

pH is a ubiquitous regulator of biological activity, including protein-folding, protein-protein interactions and enzymatic activity. Existing constant pH molecular dynamics (CPHMD) models that were developed to address questions related to the pH-dependent properties of proteins are largely based on...

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Vydáno v:Proteins
Hlavní autoři: Goh, Garrett B., Hulbert, Benjamin S., Zhou, Huiqing, Brooks, Charles L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394622/
https://ncbi.nlm.nih.gov/pubmed/24375620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24499
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