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DNA Damage: A Sensible Mediator of the Differentiation Decision in Hematopoietic Stem Cells and in Leukemia

In the adult, the source of functionally diverse, mature blood cells are hematopoietic stem cells, a rare population of quiescent cells that reside in the bone marrow niche. Like stem cells in other tissues, hematopoietic stem cells are defined by their ability to self-renew, in order to maintain th...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Weiss, Cary N., Ito, Keisuke
Format: Artigo
Language:Inglês
Published: MDPI 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394526/
https://ncbi.nlm.nih.gov/pubmed/25789504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16036183
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