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DNA Damage Response, Redox Status and Hematopoiesis

The ability of hematopoietic stem cells (HSCs) to self-renew and differentiate into progenitors is essential for homeostasis of the hematopoietic system. The longevity of HSCs makes them vulnerable to accumulating DNA damage, which may be leukemogenic or result in senescence and cell death. Addition...

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Detalhes bibliográficos
Main Authors: Weiss, Cary N., Ito, Keisuke
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006928/
https://ncbi.nlm.nih.gov/pubmed/24041596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2013.08.002
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