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The role of PML in hematopoietic and leukemic stem cell maintenance

The tumor suppressor promyelocytic leukemia (PML) was first identified as a component of PML–RARα fusion protein, one of the initiating cytogenetic abnormalities in acute promyelocytic leukemia. PML is now known to have diverse functions regulating the DNA-damage response, apoptosis, senescence, and...

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書誌詳細
主要な著者: Nakahara, Fumio, Weiss, Cary N., Ito, Keisuke
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096053/
https://ncbi.nlm.nih.gov/pubmed/24488785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-014-1518-x
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