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The role of PML in hematopoietic and leukemic stem cell maintenance
The tumor suppressor promyelocytic leukemia (PML) was first identified as a component of PML–RARα fusion protein, one of the initiating cytogenetic abnormalities in acute promyelocytic leukemia. PML is now known to have diverse functions regulating the DNA-damage response, apoptosis, senescence, and...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096053/ https://ncbi.nlm.nih.gov/pubmed/24488785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-014-1518-x |
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