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Novel Cholesterol-Based Cationic Lipids as Transfecting Agents of DNA for Efficient Gene Delivery

The design, synthesis and biological evaluation of the cationic lipid gene delivery vectors based on cholesterol and natural amino acids lysine or histidine are described. Cationic liposomes composed of the newly synthesized cationic lipids 1a or 1b and neutral lipid DOPE (1,2-dioleoyl-l-α-glycero-3...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Ju, Jia, Huan, Meng-Lei, Wan, Ning, Qiu, Hai, Zhou, Si-Yuan, Zhang, Bang-Le
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394498/
https://ncbi.nlm.nih.gov/pubmed/25768346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16035666
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