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Novel Cholesterol-Based Cationic Lipids as Transfecting Agents of DNA for Efficient Gene Delivery

The design, synthesis and biological evaluation of the cationic lipid gene delivery vectors based on cholesterol and natural amino acids lysine or histidine are described. Cationic liposomes composed of the newly synthesized cationic lipids 1a or 1b and neutral lipid DOPE (1,2-dioleoyl-l-α-glycero-3...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Ju, Jia, Huan, Meng-Lei, Wan, Ning, Qiu, Hai, Zhou, Si-Yuan, Zhang, Bang-Le
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394498/
https://ncbi.nlm.nih.gov/pubmed/25768346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16035666
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