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A Heme Oxygenase-1 Transducer Model of Degenerative and Developmental Brain Disorders

Heme oxygenase-1 (HO-1) is a 32 kDa protein which catalyzes the breakdown of heme to free iron, carbon monoxide and biliverdin. The Hmox1 promoter contains numerous consensus sequences that render the gene exquisitely sensitive to induction by diverse pro-oxidant and inflammatory stimuli. In “stress...

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Pubblicato in:Int J Mol Sci
Autori principali: Schipper, Hyman M., Song, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394483/
https://ncbi.nlm.nih.gov/pubmed/25761244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16035400
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