Astroglial Heme Oxygenase-1 and the Origin of Corpora Amylacea in Aging and Degenerating Neural Tissues

BACKGROUND: Corpora amylacea (CA) are glycoproteinaceous (predominantly glial and extracellular) inclusions that accumulate in normal aging brain and, to a greater extent, in Alzheimer disease (AD). Previous pharmacological evidence suggested that up-regulation of endogenous heme oxygenase-1 (HO-1)...

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Autores principales: Song, Wei, Zukor, Hillel, Liberman, Adrienne, Kaduri, Sagi, Arvanitakis, Zoe, Bennett, David A., Schipper, Hyman M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020524/
https://ncbi.nlm.nih.gov/pubmed/24440642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.01.006
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