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Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters

[Image: see text] Eighteen different bisphosphonates, including four clinically used bisphosphonate acids and their phosphoesters, were studied to evaluate how the bisphosphonate structure affects binding to bone. Bisphosphonates with weak bone affinity, such as clodronate, could not bind to hydroxy...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Med Chem Lett
मुख्य लेखकों: Puljula, Elina, Turhanen, Petri, Vepsäläinen, Jouko, Monteil, Maelle, Lecouvey, Marc, Weisell, Janne
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2015
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394349/
https://ncbi.nlm.nih.gov/pubmed/25893039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5004603
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