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Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
Unexpected degradation of the P-C-P bridge from novel bisphosphonate derivative 1a and known etidronate trimethyl ester (1b) has been observed under mild reaction conditions. A proposed reaction mechanism for the unexpected degradation of 1a and 1b is also reported.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238746/ https://ncbi.nlm.nih.gov/pubmed/18208588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1860-5397-4-7 |
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