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Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions

Unexpected degradation of the P-C-P bridge from novel bisphosphonate derivative 1a and known etidronate trimethyl ester (1b) has been observed under mild reaction conditions. A proposed reaction mechanism for the unexpected degradation of 1a and 1b is also reported.

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Bibliografiset tiedot
Päätekijät: Turhanen, Petri A, Vepsäläinen, Jouko J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Beilstein-Institut 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238746/
https://ncbi.nlm.nih.gov/pubmed/18208588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1860-5397-4-7
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