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Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale
Two strategies for the synthesis of the ATP (adenosine triphosphate) analogue ApppI [1-adenosin-5’-yl 3-(3-methylbut-3-enyl)triphosphoric acid diester] (1) are described. ApppI is an active metabolite of the mevalonate pathway and thus is of major biological significance. Chemically synthezised Appp...
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Publicado no: | Beilstein J Org Chem |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Beilstein-Institut
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4660979/ https://ncbi.nlm.nih.gov/pubmed/26664641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.237 |
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