A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography

Protein 3D structure can be a powerful predictor of function, but it often faces a critical roadblock at the crystallization step. Rv1738, a protein from Mycobacterium tuberculosis that is strongly implicated in the onset of nonreplicating persistence, and thereby latent tuberculosis, resisted exten...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bunker, Richard D., Mandal, Kalyaneswar, Bashiri, Ghader, Chaston, Jessica J., Pentelute, Bradley L., Lott, J. Shaun, Kent, Stephen B. H., Baker, Edward N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394262/
https://ncbi.nlm.nih.gov/pubmed/25831534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422387112
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