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Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography

The 50-residue snake venom protein l-omwaprin and its enantiomer d-omwaprin were prepared by total chemical synthesis. Radial diffusion assays were performed against Bacillus megaterium and Bacillus anthracis; both l- and d-omwaprin showed antibacterial activity against B. megaterium. The native pro...

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Detalhes bibliográficos
Main Authors: Banigan, James R, Mandal, Kalyaneswar, Sawaya, Michael R, Thammavongsa, Vilasak, Hendrickx, Antoni P A, Schneewind, Olaf, Yeates, Todd O, Kent, Stephen B H
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998720/
https://ncbi.nlm.nih.gov/pubmed/20669184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.468
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