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RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock

Histamine-induced vascular leakage is an integral component of many highly prevalent human diseases, including allergies, asthma, and anaphylaxis. Yet, how histamine induces the disruption of the endothelial barrier is not well defined. By using genetically modified animal models, pharmacologic inhi...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Mikelis, Constantinos M., Simaan, May, Ando, Koji, Fukuhara, Shigetomo, Sakurai, Atsuko, Amornphimoltham, Panomwat, Masedunskas, Andrius, Weigert, Roberto, Chavakis, Triantafyllos, Adams, Ralf, Offermanns, Stefan, Mochizuki, Naoki, Zheng, Yi, Gutkind, J. Silvio
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394241/
https://ncbi.nlm.nih.gov/pubmed/25857352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7725
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