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RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock
Histamine-induced vascular leakage is an integral component of many highly prevalent human diseases, including allergies, asthma, and anaphylaxis. Yet, how histamine induces the disruption of the endothelial barrier is not well defined. By using genetically modified animal models, pharmacologic inhi...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394241/ https://ncbi.nlm.nih.gov/pubmed/25857352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7725 |
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