RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock

Histamine-induced vascular leakage is an integral component of many highly prevalent human diseases, including allergies, asthma, and anaphylaxis. Yet, how histamine induces the disruption of the endothelial barrier is not well defined. By using genetically modified animal models, pharmacologic inhi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Mikelis, Constantinos M., Simaan, May, Ando, Koji, Fukuhara, Shigetomo, Sakurai, Atsuko, Amornphimoltham, Panomwat, Masedunskas, Andrius, Weigert, Roberto, Chavakis, Triantafyllos, Adams, Ralf, Offermanns, Stefan, Mochizuki, Naoki, Zheng, Yi, Gutkind, J. Silvio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394241/
https://ncbi.nlm.nih.gov/pubmed/25857352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7725
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