Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells

5-Fluorouracil (FU) is a halogenated nucleobase analog that is widely used in chemotherapy. Here we show that 5-hydroxymethyl-2′-deoxyuridine (hmUdR) synergistically enhances the activity of FU in cell lines derived from solid tumors but not normal tissues. While the cytotoxicity of FU and hmUdR was...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Matsumoto, Yoshihiro, Rodriguez, Victoria, Whitford, Tracy A., Beeharry, Neil, Ide, Hiroshi, Tomkinson, Alan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394133/
https://ncbi.nlm.nih.gov/pubmed/25897430
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados