Targeted blockade of JAK/STAT3 signaling inhibits ovarian carcinoma growth

Ovarian carcinoma (OC) is the fifth leading cause of death among women in the United States. Persistent activation of signal transducer and activator of transcription (STAT3) is frequently detected in OC. STAT3 is activated by Janus family kinases (JAK) via cytokine receptors, growth factor receptor...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Ther
Asıl Yazarlar: Gritsina, Galina, Xiao, Fang, O'Brien, Shane W., Gabbasov, Rashid, Maglaty, Marisa A., Xu, Ren-Huan, Thapa, Roshan J., Zhou, Yan, Nicolas, Emmanuelle, Litwin, Samuel, Balachandran, Siddharth, Sigal, Luis J., Huszar, Dennis, Connolly, Denise C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394029/
https://ncbi.nlm.nih.gov/pubmed/25646015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0800
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