PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper

Poorly-defined interactions between environmental and genetic risk factors underlie Parkinson’s disease (PD) etiology. Here we tested the hypothesis that human stem cell derived forebrain neuroprogenitors from patients with known familial risk for early onset PD will exhibit enhanced sensitivity to...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Aboud, Asad A., Tidball, Andrew M., Kumar, Kevin K., Neely, M. Diana, Han, Bingying, Ess, Kevin C., Hong, Charles C., Erikson, Keith M., Hedera, Peter, Bowman, Aaron B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394022/
https://ncbi.nlm.nih.gov/pubmed/25315681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.10.002
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