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Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference

Anti-angiogenic therapies target the tumor vasculature, impairing its development and growth. It was hypothesized over 40 years ago by the late Judah Folkman and Julie Denekamp that depriving a tumor of oxygen and nutrients, by targeting the tumor vasculature, could have therapeutic benefits. Identi...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Biel, Nikolett M., Siemann, Dietmar W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394020/
https://ncbi.nlm.nih.gov/pubmed/25312939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.035
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