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Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference
Anti-angiogenic therapies target the tumor vasculature, impairing its development and growth. It was hypothesized over 40 years ago by the late Judah Folkman and Julie Denekamp that depriving a tumor of oxygen and nutrients, by targeting the tumor vasculature, could have therapeutic benefits. Identi...
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Udgivet i: | Cancer Lett |
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Main Authors: | , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394020/ https://ncbi.nlm.nih.gov/pubmed/25312939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.035 |
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