AI-26 OVERCOMING RESISTANCE TO VEGF-BLOCKADE BY TARGETING THE ANGIOPOIETIN/TIE2 AXIS

Angiogenesis inhibitors have evolved in the past decade as one of the most promising biology based therapeutic strategies. Pre-clinical studies (published in 1993 and 1994) provided proof of principle that blocking of VEGF dramatically inhibits tumor growth. These observations led to the successful...

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Hauptverfasser: Scholz, Alexander, Cremer, Sebastian, Harter, Patrick, Mittelbronn, Michel, van Slyke, Paul, Dumont, Dan, Plate, Karl H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217865/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou238.26
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