MOVING BEYOND VEGF: INHIBING GLIOMA ANGIOGENESIS BY TARGETING THE TIE2/ANGIOPOIETIN SIGNALING PATHWAY

BACKGROUND: Angiogenesis inhibitors have evolved in the past decade as one of the most promising biology based therapeutic strategies. Promising pre-clinical studies (published in 1993 and 1994) provided proof of principle that blocking of VEGF dramatically inhibits tumor growth. These observations...

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書誌詳細
主要な著者: Plate, Karl H., Scholz, Alexander, Mittelbronn, Michel, Harter, Patrick, Dumont, Daniel, van Slyke, Paul, Reiss, Yvonne
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
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abstracts
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144523/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.55
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