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MOVING BEYOND VEGF: INHIBING GLIOMA ANGIOGENESIS BY TARGETING THE TIE2/ANGIOPOIETIN SIGNALING PATHWAY
BACKGROUND: Angiogenesis inhibitors have evolved in the past decade as one of the most promising biology based therapeutic strategies. Promising pre-clinical studies (published in 1993 and 1994) provided proof of principle that blocking of VEGF dramatically inhibits tumor growth. These observations...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144523/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.55 |
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