Generation of food-grade recombinant Lactobacillus casei delivering Myxococcus xanthus prolyl endopeptidase

Prolyl endopeptidases (PEP), a family of serine proteases with the ability to hydrolyze the peptide bond on the carboxyl side of an internal proline residue, are able to degrade immunotoxic peptides responsible for celiac disease (CD), such as a 33-residue gluten peptide (33-mer). Oral administratio...

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Pubblicato in:Appl Microbiol Biotechnol
Autori principali: Alvarez-Sieiro, Patricia, Martin, Maria Cruz, Redruello, Begoña, del Rio, Beatriz, Ladero, Victor, Palanski, Brad A., Khosla, Chaitan, Fernandez, Maria, Alvarez, Miguel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393947/
https://ncbi.nlm.nih.gov/pubmed/24752841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-014-5730-7
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