Type I Saikosaponins A and D Inhibit Osteoclastogenesis in Bone Marrow-Derived Macrophages and Osteolytic Activity of Metastatic Breast Cancer Cells

Many osteopenic disorders, including a postmenopausal osteoporosis and lytic bone metastasis in breast and prostate cancers, are linked with a hyperosteoclast activity due to increased receptor activator of nuclear factor kappa-B ligand (RANKL) expression in osteoblastic/stromal cells. Therefore, in...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Shin, Ji-Eun, Kim, Hyun-Jeong, Kim, Ki-Rim, Lee, Sun Kyoung, Park, Junhee, Kim, Hyungkeun, Park, Kwang-Kyun, Chung, Won-Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393913/
https://ncbi.nlm.nih.gov/pubmed/25892999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/582437
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