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Rat aortic smooth muscle cells cultured on hydroxyapatite differentiate into osteoblast-like cells via BMP2 -SMAD5 pathway

Vascular calcification is an important pathological condition associated with increased risk of cardiovascular mortality. Hydroxyapatite (HA) found in such deposits is the same polymorph of calcium (Ca) found in bone, indicating calcification may involve mechanisms akin to bone formation. Vascular s...

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Detalhes bibliográficos
Publicado no:Calcif Tissue Int
Main Authors: Nahar-Gohad, Pranjal, Gohad, Neeraj, Tsai, Chen-Chih, Bordia, Rajendra, Vyavahare, Naren
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393885/
https://ncbi.nlm.nih.gov/pubmed/25725805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-015-9962-z
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