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The STING pathway and the T cell-inflamed tumor microenvironment

A major subset of patients with advanced solid tumors shows a spontaneous T cell-inflamed tumor microenvironment, which has prognostic import and is associated with clinical response to immunotherapies. As such, understanding the mechanisms governing the generation of spontaneous T cell responses in...

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Publicat a:Trends Immunol
Autors principals: Woo, Seng-Ryong, Corrales, Leticia, Gajewski, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393801/
https://ncbi.nlm.nih.gov/pubmed/25758021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.02.003
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