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An NAD Synthetic Reaction Bypasses the Lipoate Requirement for Aerobic Growth of Escherichia coli Strains Blocked in Succinate Catabolism
The lipoate coenzyme is essential for function of the pyruvate (PDH) and 2-oxoglutarate (OGDH) dehydrogenases and thus for aerobic growth of Escherichia coli. LipB catalyzes the first step in lipoate synthesis, transfer of an octanoyl moiety from the fatty acid synthetic intermediate, octanoyl-ACP,...
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| Veröffentlicht in: | Mol Microbiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4393350/ https://ncbi.nlm.nih.gov/pubmed/25303731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12822 |
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