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Regulation of soluble fms-like tyrosine kinase-1 production in response to placental ischemia/hypoxia: role of angiotensin II

While soluble fms-like tyrosine-1 (sFlt-1) is implicated in the pathogenesis of hypertension during preeclampsia, the mechanisms leading to the enhanced sFlt-1 production remain unclear. A recent report suggests exogenous angiotensin II (ANGII) stimulates sFlt-1 production in pregnant rats, however,...

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Détails bibliographiques
Publié dans:Physiol Rep
Auteurs principaux: Murphy, Sydney R, Cockrell, Kathy
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393214/
https://ncbi.nlm.nih.gov/pubmed/25716926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12310
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