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Association of the ACTN3 R557X polymorphism with glucose tolerance and gene expression of sarcomeric proteins in human skeletal muscle

A common polymorphism (R577X) in the α-actinin (ACTN) 3 gene, which leads to complete deficiency of a functional protein in skeletal muscle, could directly influence metabolism in the context of health and disease. Therefore, we tested the hypothesis that states of glucose tolerance are associated w...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Riedl, Isabelle, Osler, Megan E, Benziane, Boubacar, Chibalin, Alexander V, Zierath, Juleen R
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393151/
https://ncbi.nlm.nih.gov/pubmed/25780092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12314
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