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Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle

In mammals, the sestrin family is composed of three stress-responsive genes. Ablation of sestrin in Drosophila attenuates longevity, which is accompanied by increased S6K phosphorylation and decreased AMPK phosphorylation. Nevertheless, the metabolic role of sestrins in mammals is not comprehensivel...

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Détails bibliographiques
Auteurs principaux: Nascimento, Emmani BM, Osler, Megan E., Zierath, Juleen R.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882372/
https://ncbi.nlm.nih.gov/pubmed/24129397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00212.2013
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