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Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle

In mammals, the sestrin family is composed of three stress-responsive genes. Ablation of sestrin in Drosophila attenuates longevity, which is accompanied by increased S6K phosphorylation and decreased AMPK phosphorylation. Nevertheless, the metabolic role of sestrins in mammals is not comprehensivel...

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Библиографические подробности
Главные авторы: Nascimento, Emmani BM, Osler, Megan E., Zierath, Juleen R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882372/
https://ncbi.nlm.nih.gov/pubmed/24129397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00212.2013
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