Diacylglycerol kinase-δ regulates AMPK signaling, lipid metabolism, and skeletal muscle energetics

Decrease of AMPK-related signal transduction and insufficient lipid oxidation contributes to the pathogenesis of obesity and type 2 diabetes. Previously, we identified that diacylglycerol kinase-δ (DGKδ), an enzyme involved in triglyceride biosynthesis, is reduced in skeletal muscle from type 2 diab...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Jiang, Lake Q., de Castro Barbosa, Thais, Massart, Julie, Deshmukh, Atul S., Löfgren, Lars, Duque-Guimaraes, Daniella E., Ozilgen, Arda, Osler, Megan E., Chibalin, Alexander V., Zierath, Juleen R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675797/
https://ncbi.nlm.nih.gov/pubmed/26530149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00209.2015
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