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Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle
In mammals, the sestrin family is composed of three stress-responsive genes. Ablation of sestrin in Drosophila attenuates longevity, which is accompanied by increased S6K phosphorylation and decreased AMPK phosphorylation. Nevertheless, the metabolic role of sestrins in mammals is not comprehensivel...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882372/ https://ncbi.nlm.nih.gov/pubmed/24129397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00212.2013 |
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