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Protein kinase N2 regulates AMP kinase signaling and insulin responsiveness of glucose metabolism in skeletal muscle

Insulin resistance is central to the development of type 2 diabetes and related metabolic disorders. Because skeletal muscle is responsible for the majority of whole body insulin-stimulated glucose uptake, regulation of glucose metabolism in this tissue is of particular importance. Although Rho GTPa...

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Détails bibliographiques
Publié dans:Am J Physiol Endocrinol Metab
Auteurs principaux: Ruby, Maxwell A., Riedl, Isabelle, Massart, Julie, Åhlin, Marcus, Zierath, Juleen R.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668594/
https://ncbi.nlm.nih.gov/pubmed/28720584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00147.2017
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