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Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts

BACKGROUND: Shb is a signaling protein downstream of vascular endothelial growth factor receptor-2 and Shb deficiency has been found to restrict tumor angiogenesis. The present study was performed in order to assess metastasis in Shb deficiency using B16F10 melanoma cells. METHODS: B16F10 melanoma c...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Zang, Guangxiang, Gustafsson, Karin, Jamalpour, Maria, Hong, JongWook, Genové, Guillem, Welsh, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392795/
https://ncbi.nlm.nih.gov/pubmed/25885274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1269-y
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