Regular Article Macroautophagy is Defective in Mucolipin 1-Deficient Mouse Neurons

Mucolipidosis Type IV is a neurodegenerative lysosomal disease clinically characterized by psychomotor retardation, visual impairment, and achlorhydria. In this study we report the development of a neuronal cell model generated from cerebrum of Mcoln1(-/-) embryos. Prior functional characterization...

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Détails bibliographiques
Publié dans:Neurobiol Dis
Auteurs principaux: Curcio-Morelli, Cyntia, Charles, Florie A., Micsenyi, Matthew C., Cao, Yi, Venugopal, Bhuvarahamurthy, Browning, Marsha F., Dobrenis, Kostantin, Cotman, Susan L., Walkley, Steven U., Slaugenhaupt, Susan A.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392647/
https://ncbi.nlm.nih.gov/pubmed/20600908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.06.010
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