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Lysosomal Compromise and Brain Dysfunction: Examining the Role of Neuroaxonal Dystrophy

Lysosomal diseases are a family of over 50 disorders caused by defects in proteins critical for normal function of the endosomal/lysosomal system and characterized by complex pathogenic cascades involving progressive dysfunction of many organ systems, most notably brain. Evidence suggests that compr...

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Dettagli Bibliografici
Pubblicato in:Biochem Soc Trans
Autori principali: Walkley, Steven U., Sikora, Jakub, Micsenyi, Matthew, Davidson, Cristin, Dobrenis, Kostantin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406245/
https://ncbi.nlm.nih.gov/pubmed/21118103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0381436
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