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Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter
The SLC22A1 influx transporter is expressed on the basolateral membrane of hepatocytes and is involved in the excretion of numerous cations. Inhibition of SLC22A1 by several antiretrovirals, such as the protease inhibitor darunavir, has not previously been determined. In order to better understand a...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392609/ https://ncbi.nlm.nih.gov/pubmed/25914645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00078 |
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