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Non-cell autonomous effects of targeting inducible PGE(2) synthesis during inflammation-associated colon carcinogenesis
Microsomal PGE(2) synthase-1 (mPGES-1), the terminal enzyme in the formation of inducible PGE(2), represents a potential target for cancer chemoprevention. We have previously shown that genetic abrogation of mPGES-1 significantly suppresses tumorigenesis in two preclinical models of intestinal cance...
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| Veröffentlicht in: | Carcinogenesis |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392604/ https://ncbi.nlm.nih.gov/pubmed/25634334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv004 |
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