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Selective PGE(2) suppression impairs colon carcinogenesis and modifies local mucosal immunity
Prostaglandin E(2) (PGE(2)) is a bioactive lipid that mediates a wide range of physiological effects and plays a central role in inflammation and cancer. PGE(2) is generated from arachidonic acid by the sequential actions of the cyclooxygenases (COXs) and terminal synthases (PGES). Increased levels...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151318/ https://ncbi.nlm.nih.gov/pubmed/21576350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0188 |
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