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Suppression of colon carcinogenesis by targeting Notch signaling

Recent studies have shown that aberrant Notch signaling contributes to the pathogenesis of colorectal cancer (CRC). However, the potential therapeutic benefits of Notch pathway inhibitors, including gamma-secretase inhibitors (GSIs) on colon carcinogenesis are still unclear. In this study, the effec...

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Detalhes bibliográficos
Main Authors: Miyamoto, Shingo, Nakanishi, Masako, Rosenberg, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786381/
https://ncbi.nlm.nih.gov/pubmed/23729655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt191
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