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Suppression of colon carcinogenesis by targeting Notch signaling

Recent studies have shown that aberrant Notch signaling contributes to the pathogenesis of colorectal cancer (CRC). However, the potential therapeutic benefits of Notch pathway inhibitors, including gamma-secretase inhibitors (GSIs) on colon carcinogenesis are still unclear. In this study, the effec...

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Bibliografske podrobnosti
Main Authors: Miyamoto, Shingo, Nakanishi, Masako, Rosenberg, Daniel W.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786381/
https://ncbi.nlm.nih.gov/pubmed/23729655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt191
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