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Suppression of colon carcinogenesis by targeting Notch signaling

Recent studies have shown that aberrant Notch signaling contributes to the pathogenesis of colorectal cancer (CRC). However, the potential therapeutic benefits of Notch pathway inhibitors, including gamma-secretase inhibitors (GSIs) on colon carcinogenesis are still unclear. In this study, the effec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Miyamoto, Shingo, Nakanishi, Masako, Rosenberg, Daniel W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786381/
https://ncbi.nlm.nih.gov/pubmed/23729655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt191
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