Intronic TP53 Germline Sequence Variants Modify the Risk in German Breast/Ovarian Cancer Families

To establish the contribution of TP53 germline mutations to familial breast/ovarian cancer in Germany we screened the complete coding region of the TP53 gene in a series of German breast/ovarian cancer families negative for mutations in the BRCA1 and BRCA2 genes. Two different intronic TP53 sequence...

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Bibliographic Details
Published in:Hered Cancer Clin Pract
Main Authors: Liu, Xuan, Sinn, Hans-Peter, Ulmer, Hans Ulrich, Scott, Rodney J, Hamann, Ute
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392522/
https://ncbi.nlm.nih.gov/pubmed/20233468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-2-3-139
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