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Increased H(+) efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression

Intracellular pH (pHi) dynamics is increasingly recognized as an important regulator of a range of normal and pathological cell behaviors. Notably, increased pHi is now acknowledged as a conserved characteristic of cancers and in cell models is confirmed to increase proliferation and migration as we...

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Pubblicato in:eLife
Autori principali: Grillo-Hill, Bree K, Choi, Changhoon, Jimenez-Vidal, Maite, Barber, Diane L
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392478/
https://ncbi.nlm.nih.gov/pubmed/25793441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03270
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