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Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation

Despite extensive knowledge about the transcriptional regulation of stem cell differentiation, less is known about the role of dynamic cytosolic cues. We report that an increase in intracellular pH (pHi) is necessary for the efficient differentiation of Drosophila adult follicle stem cells (FSCs) an...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Ulmschneider, Bryne, Grillo-Hill, Bree K., Benitez, Marimar, Azimova, Dinara R., Barber, Diane L., Nystul, Todd G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100294/
https://ncbi.nlm.nih.gov/pubmed/27821494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606042
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